IRE1alpha kinase-IN-1 is a highly selective IRE1alpha (ERN1) inhibitor, with an IC50 of 77 nM. IRE1alpha kinase-IN-1 displays 100-fold selectivity for IRE1alpha over the IRE1beta isoform. IRE1alpha kinase-IN-1 inhibits ER stress-induced IRE1alpha oligomerization and autophosphoryl
Molecular Weight:
504.99
Purity:
99.44
CAS Number:
[2328097-41-0]
Formula:
C26H26ClFN8
Target:
IRE1
Application Notes:
Reference compound
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