Tuxobertinib (BDTX-189) is a potent, orally active and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, including EGFR/HER2 exon 20 insertion mutants. Tuxobertinib shows KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, r
Molecular Weight:
561.03
Purity:
99.94
CAS Number:
[2414572-47-5]
Formula:
C29H29ClN6O4
Target:
EGFR
Application Notes:
Reference compound
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