PQ401 is a potent inhibitor of IGF-IR signaling. PQ401 inhibits IGF-I-stimulated IGF-IR autophosphorylation with an IC50 of 12.0 µM in a series of studies in MCF-7 cells. PQ401 is effective at inhibiting IGF-I-stimulated growth of MCF-7 cells (IC50, 6 µM
Molecular Weight:
341.79
Purity:
99.85
CAS Number:
[196868-63-0]
Formula:
C18H16ClN3O2
Target:
Apoptosis,IGF-1R
Application Notes:
Reference compound
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