TM-1 is a potent inhibitor of pyruvate dehydrogenase kinase (PDHK1). TM-1 inhibits PDHK1 and PDHK2 with IC50s of 2.97 µM and 5.2 µM, respectively. TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation, and inhibits cell proliferation[1].
Molecular Weight:
468.54
Purity:
95.04
CAS Number:
[921099-13-0]
Formula:
C26H32N2O6
Target:
PDHK
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
