AZ12672857 is an orally active inhibitor of EphB4 (IC50=1.3 nM) and Src kinases. AZ12672857 shows good inhibition of proliferation of c-Src transfected 3T3 cells (IC50=2 nM) as well as autophosphorylation of EphB4 in transfected CHO-K1 cells (IC50=9 nM)[
Molecular Weight:
486.57
Purity:
98.44
CAS Number:
[945396-55-4]
Formula:
C26H30N8O2
Target:
Prostaglandin Receptor
Application Notes:
Reference compound
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