TAS-119 is a potent, selective and orally active Aurora A inhibitor with an IC50 of 1.0 nM. TAS-119 shows high selectivity for Aurora A over other protein kinases, including Aurora B (IC50 of 95 nM). TAS-119 has potent antitumor activites[1].
Molecular Weight:
506.36
Purity:
98.03
CAS Number:
[1453099-83-6]
Formula:
C23H22Cl2FN5O3
Target:
Aurora Kinase
Application Notes:
Reference compound
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