PLX647 is an orally active, highly specific dual FMS and KIT kinase inhibitor, with IC50s of 28 and 16 nM, respectively. PLX647 shows selectivity for FMS and KIT over a panel of 400 kinases at a concentration of 1 µM except FLT3 and KDR (IC50s=91 and 130
Molecular Weight:
382.38
Purity:
99.79
CAS Number:
[873786-09-5]
Formula:
C21H17F3N4
Target:
c-Fms,c-Kit
Application Notes:
Reference compound
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