HPK1-IN-3 is a potent and selective ATP-competitive hematopoietic progenitor kinase 1 (HPK1, MAP4K1) inhibitor with an IC50 of 0.25 nM. HPK1-IN-3 has IL-2 cellular potency with an EC50 of 108 nM in human peripheral blood mononuclear cells (PBMCs)[1].
Molecular Weight:
490.45
Purity:
99.32
CAS Number:
[2739844-34-7]
Formula:
C23H22F4N6O2
Target:
MAP4K
Application Notes:
Reference compound
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