AY77 is a calcium-biased PAR2 agonist. AY77 shows an EC50 of 0.17 and 2 nM in PAR2-mediated the activation in the Gq pathway and recruitment of beta-arrestin-2, respectively. AY77 potently induces intracellular Ca2+ release[1][2].
Molecular Weight:
404.50
CAS Number:
[1835734-92-3]
Formula:
C21H32N4O4
Target:
Protease Activated Receptor (PAR)
Application Notes:
Peptides
* VAT and and shipping costs not included. Errors and price changes excepted