JW 55 is a potent and selective beta-catenin signaling pathway inhibitor, which functions via inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2). JW 55 decreases auto-PARsylation of TNKS1/2 in vitro with IC50s of 1.9 µM and 830 nM respec
Molecular Weight:
434.48
Purity:
98.95
CAS Number:
[664993-53-7]
Formula:
C25H26N2O5
Target:
PARP
Application Notes:
Reference compound
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