JAK-IN-20 is a potent, pan and orally active JAK inhibitor with an IC50s of 7 nM, 5 nM, 14 nM for JAK1, JAK2, JAK3, respectively. JAK-IN-20 shows excellent pharmacokinetics and displays anti-inflammatory efficacy in vivo[1].
Molecular Weight:
515.58
CAS Number:
[1654776-91-6]
Formula:
C28H30FN7O2
Target:
JAK
Application Notes:
Reference compound
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