GSK-25 is a potent, selective and orally bioavailable ROCK1 inhibitor (IC50=7 nM). GSK-25 maintains good selectivity against a panel of 31 kinases (>100 fold), as well as RSK1 and p70S6K (RSK1: IC50=398 nM, p70S6K: IC50=1 µM). GSK-25 inhibits P450 profil
Molecular Weight:
513.33
Purity:
99.68
CAS Number:
[874119-56-9]
Formula:
C24H16Cl2F2N6O
Target:
Ribosomal S6 Kinase (RSK),ROCK
Application Notes:
Reference compound
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