RET-IN-11 is a potent and selective RET inhibitor with IC50s of 6.20 nM, 18.68 nM for RET and RETV804M, respectively. RET-IN-11 shows anti-proliferation and migration activity in CCDC6-RET-driven LC-2/ad cells. RET-IN-11 induces cell apoptosis[1].
Molecular Weight:
515.59
CAS Number:
[2764891-88-3]
Formula:
C27H30FN9O
Target:
Apoptosis,RET
Application Notes:
Reference compound
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