SHR902275 is a potent, selective, and orally active RAF inhibitor targeting RAS mutant cancers. SHR902275 has IC50s of 1.6 nM, 10 nM, and 5.7 nM for cRAF, bRAFwt, and bRAFV600E, respectively. SHR902275 shows cell growth inhibition with GI50s of 1.5 and 0
Molecular Weight:
512.48
CAS Number:
[2695506-82-0]
Formula:
C26H23F3N4O4
Target:
Raf
Application Notes:
Reference compound
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