Pyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC50s of 1 nM for JAK2 and TYK2, 5 nM for JAK3, and 15 nM for JAK1, while displaying significantly weaker affinities (130 nM to >10 mM) for other protein tyrosine kina
Molecular Weight:
309.34
Purity:
98.13
CAS Number:
[457081-03-7]
Formula:
C18H16FN3O
Target:
JAK
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted