SHP2-IN-8 is a highly potent, selective, and cellularly active allosteric SHP2 inhibitor with IC50 value of 23 nM and Ki of 22 nM. SHP2-IN-8 is reversible and noncompetitive. SHP2-IN-8 causes a significant thermal shift with the deltaTm of 7.01 °C. SHP2-IN-8
Molecular Weight:
398.35
CAS Number:
[1801692-60-3]
Formula:
C17H21Cl2N5S
Target:
Akt,Apoptosis,Phosphatase,SHP2
Application Notes:
Reference compound
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