Trk-IN-10 (Compound 14j) is a potent inhibitor of TRK (IC50 = 0.86, 6.92 nM, against TrkA, TrkAG595R, respectively). As a receptor tyrosine kinase (RTK), tropomyosin receptor kinase (Trk) is a key agent target in solid tumors. Trk-IN-10 (IC50 = 350 nM ag
Molecular Weight:
397.4
CAS Number:
[2700265-61-6]
Formula:
C20H20FN5O3
Target:
Trk Receptor
Application Notes:
Reference compound
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