D18 is an immune modulator. D18 acts as a TLR7/8 dual agonist (EC50=24 nM for hTLR7 and 10 nM for hTLR8, respectively). D18 increases PD-L1 expression through epigenetic regulation, thus sensitizing tumors to PD-1/PD-L1 blockade. D18 is a ADC cytotoxin u
Molecular Weight:
364.49
Purity:
98.79
CAS Number:
[2230218-36-5]
Formula:
C21H28N6
Target:
PD-1/PD-L1,Toll-like Receptor (TLR)
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
