TLR7/8 antagonist 2 (Compound 15) is a potent and orally active agonist of TLR7/8 with IC50s of 4.9 and 0.6 nM, respectively. Inappropriate activation of TLR7 and TLR8 is linked to several autoimmune diseases, such as lupus erythematosus. TLR7/8 antagoni
Molecular Weight:
379.47
Purity:
99.68
CAS Number:
[2769085-03-0]
Formula:
C22H26FN5
Target:
Toll-like Receptor (TLR)
Application Notes:
Reference compound
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