DDO-7263, a 1,2,4-Oxadiazole derivative, is a potent Nrf2-ARE activator. DDO-7263 upregulates Nrf2 through binding to Rpn6 to block the assembly of 26S proteasome and the subsequent degradation of ubiquitinated Nrf2. DDO-7263 induces Nrf2 translocation i
Molecular Weight:
273.24
Purity:
99.63
CAS Number:
[2254004-96-9]
Formula:
C14H9F2N3O
Target:
Keap1-Nrf2
Application Notes:
Reference compound
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