KIRA9 is a potent IRE1 inhibitor (IC50=4.8 µM in INS-1 cells). KIRA9 is able to fully engage the ATP-binding site of IRE1alpha. KIRA9 can block ER-localized mRNA decay and apoptosis[1].
Molecular Weight:
572.60
CAS Number:
[2922507-65-9]
Formula:
C27H27F3N6O3S
Target:
Apoptosis,IRE1
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
