MRTX-EX185 is a potent inhibitor of GDP-loaded KRAS and KRAS(G12D), with an IC50 of 90 nM for KRAS(G12D). MRTX-EX185 also binds GDP-loaded HRAS[1]. MRTX-EX185 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azid
Molecular Weight:
564.65
Formula:
C33H33FN6O2
Target:
Ras
Application Notes:
Reference compound
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