MRTX-EX185 formic is a potent inhibitor of GDP-loaded KRAS and KRAS(G12D), with an IC50 of 90 nM for KRAS(G12D). MRTX-EX185 formic also binds GDP-loaded HRAS[1]. MRTX-EX185 (formic) is a click chemistry reagent, it contains an Alkyne group and can underg
Molecular Weight:
610.68
Purity:
97.32
Formula:
C34H35FN6O4
Target:
Ras
Application Notes:
Reference compound
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