GSK761 is a selective inhibitor of speckled 140 kDa (SP140) with an IC50 value of 77.79 nM. GSK761 reduces monocyte-to-inflammatory macrophage differentiation and lipopolysaccharide (LPS)-induced inflammatory activation. GSK761 induces the production of
Molecular Weight:
646.82
Purity:
99.64
Formula:
C40H46N4O4
Target:
Epigenetic Reader Domain
Application Notes:
Reference compound
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