KH-4-43 is an inhibitor of E3 CRL4. KH-4-43 inhibits E3 CRL4s core ligase complex and exhibits anticancer activity. KH-4-43 has a binding Kd to E3 ROC1-CUL4A CTD or the highly related ROC1-CUL1 CTD at 83 nM or 9.4 µM, respectively[1].
Molecular Weight:
422.74
Purity:
99.99
CAS Number:
[2813310-07-3]
Formula:
C19H10ClF3N2O4
Target:
Others
Application Notes:
Reference compound
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