BPA-B9 is a RXRalpha ligand and antagonist targeting the pRXRalpha-PLK1 interaction. BPA-B9 has excellent RXRalpha-binding affinity (KD=39.29 1.12 nM). BPA-B9 inhibits the proliferation of cancer cells by inducing mitotic arrest and cell apoptosis[1].
Molecular Weight:
414.50
Formula:
C25H26N4O2
Target:
Apoptosis,Bcl-2 Family,PARP,RAR/RXR
Application Notes:
Reference compound
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