RET-IN-22 (compound 17b) is a potent, selective and orally active RET inhibitor with an IC50 of 20.9 nM and 18.3 nM for wild-type RET and RET-V804M, respectively. RET-IN-22 shows highly selective profile to most kinases, especially to EGFR and VEGFR2. RE
Molecular Weight:
584.59
CAS Number:
[2918281-79-3]
Formula:
C29H31F3N6O4
Target:
RET
Application Notes:
Reference compound
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