JNJ-28583113 is an TRPM2 antagonist with brain permeability. JNJ-28583113 inhibits TRPM2 blocked phosphorylation of GSK3alpha and beta subunits. JNJ-28583113 protects cells from oxidative stress induced cell death. JNJ-28583113 also suppresses cytokine release
Molecular Weight:
366.38
Purity:
98.06
CAS Number:
[2765255-93-2]
Formula:
C19H21F3N2O2
Target:
TRP Channel
Application Notes:
Reference compound
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