LL-K8-22 is a potent, selective and durable CDK8-cyclin C dual degrader, with DC50 values of 2.52 and 2.64 µM, respectively. LL-K8-22 also suppresses STAT1 Ser 727 phosphorylation. LL-K8-22 inhibits E2F- and MYC-driven carcinogenic transcriptional progra
Molecular Weight:
573.77
Purity:
99.76
Formula:
C37H43N5O
Target:
CDK,Early 2 Factor (E2F),STAT
Application Notes:
Reference compound
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