AChE/BChE-IN-12 (compound 10b), a 3,5-dimethoxy analogue, is a potent AChE, BChE, and beta-secretase-1 (BACE-1) inhibitor, with IC50 values of 2.57, 3.26, and 10.65 µM, respectively. AChE/BChE-IN-12 crosses the blood-brain barrier via passive diffusion and
Molecular Weight:
435.43
Formula:
C23H21N3O6
Target:
Amyloid-beta,Beta-secretase,Cholinesterase (ChE)
Application Notes:
Reference compound
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