MDMX/MDM2-IN-2 is a potent p53-MDM2/MDMX dual inhibitors with Kis of 0.23 µM and 2.45 µM for MDM2 and MDMX, respectively. MDMX/MDM2-IN-2 inhibits the binding of p53 and MDM2 proteins. MDMX/MDM2-IN-2 restores the function of p53 and enables cell cycle arr
Molecular Weight:
576.87
Formula:
C28H25Cl3FN3O3
Target:
Apoptosis,MDM-2/p53
Application Notes:
Reference compound
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