PTP1B/AKR1B1-IN-2 (Compound 7f) is a dual PTP1B/AKR1B1 inhibitor (IC50s: 3.2 and 2.1 µM, Kis: 4.0 and 0.9µM). PTP1B/AKR1B1-IN-2 is an insulin-mimetic agent. PTP1B/AKR1B1-IN-2 improves glucose uptake in murine C2C12 myoblasts. PTP1B/AKR1B1-IN-2 can be use
Molecular Weight:
441.56
Formula:
C23H23NO4S2
Target:
Aldose Reductase,Phosphatase
Application Notes:
Reference compound
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