PKM2/PDK1-IN-1, one of shikonin thioether derivatives, is a dual inhibitor of PKM2/PDK1. PKM2/PDK1-IN-1 inhibits the proliferation of NSCLC cells, and induces apoptosis. PKM2/PDK1-IN-1 induces intercellular ROS production, and regulates the apoptotic pro
Molecular Weight:
697.92
Formula:
C36H43NO7S3
Target:
Akt,Apoptosis,EGFR,PDK-1,Pyruvate Kinase
Application Notes:
Reference compound
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