FM04 is a potent P-glycoprotein (P-gp) inhibitor (EC50=83 nM). FM04 inhibits P-gp in 2 mechanism: (1)FM04 binds to Q1193, followed by interacting with the functionally critical residues H1195 and T1226, or (2)FM04 binds to I1115 (a functionally critical
Molecular Weight:
415.48
CAS Number:
[1807320-40-6]
Formula:
C26H25NO4
Target:
P-glycoprotein
Application Notes:
Reference compound
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