hAChE/hBACE-1-IN-1 (compounds 5d) is an orally active inhibitor of hAChE with blood-brain permeability. hAChE/hBACE-1-IN-1 inhibits hAChE and hBACE-1 with IC50 values of 0.076 and 0.23 µM, respectively. hAChE/hBACE-1-IN-1 inhibits Abeta1-42 aggregation and
Molecular Weight:
433.53
Formula:
C23H23N5O2S
Target:
Cholinesterase (ChE)
Application Notes:
Reference compound
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