SR-4133 is a potent and highly CK1epsilon selective inhibitor with an IC50 of 58 nM. SR-4133 binds to the ATP-binding site of CK1epsilon. SR-4133 displays nanomolar growth inhibition of bladder cancer cells, and inhibits the phosphorylation of 4E-BP1[1].
Molecular Weight:
512.51
CAS Number:
[2999645-23-5]
Formula:
C27H22F2N8O
Target:
Casein Kinase
Application Notes:
Reference compound
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