MS78 is an acetylation targeting chimera (AceTAC) that acetylates the p53 tumor suppressor protein. MS78 recruits histone acetyltransferase p300/CBP to acetylate the p53Y220C mutant. MS78 upregulates TRAIL apoptotic genes and downregulates DNA damage res
Molecular Weight:
1024.25
Formula:
C57H66FN9O6S
Target:
Histone Acetyltransferase,MDM-2/p53
Application Notes:
Reference compound
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