IHMT-IDH1-053 (compound 16) is a highly selectivity and irreversible IDH1-mutant inhibitor with an IC50 of 4.7 nM for IDH1 R132H. IHMT-IDH1-053 displays high selectivity against IDH1 mutants over IDH1 wt and IDH2 wt/mutants. IHMT-IDH1-053 inhibits 2-hydr
Molecular Weight:
532.63
Formula:
C25H33FN6O4S
Target:
Isocitrate Dehydrogenase (IDH)
Application Notes:
Reference compound
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