SIKs-IN-1 (compound 8h), a pyrimidine-5-carboxamide derivative, is a Salt-inducible kinases (SIKs) inhibitor. SIKs regulates the transformation of M1/M2 macrophages, involving in inflammation process. SIKs-IN-1 inhibits SIK activity, up-regulates anti-in
Molecular Weight:
507.58
CAS Number:
[2927557-06-8]
Formula:
C27H31F2N7O
Target:
Salt-inducible Kinase (SIK)
Application Notes:
Reference compound
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