D3R/MOR antagonist 2 (Compound 121) is a D3R/MOR antagonist (Ki: 361 nM and 85.2 nM respectively). D3R/MOR antagonist 2 has the potential to produce analgesic effects through MOR partial agonism, reduce opioid-misuse liability via D3R antagonism[1].
Molecular Weight:
410.98
Formula:
C25H31ClN2O
Target:
Dopamine Receptor,Opioid Receptor
Application Notes:
Reference compound
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