NDNA3 (compound 14) is a selective inhibitor of Hsp90alpha (IC50: 0.51 µM). NDNA3 is a permanently charged analog with low membrane permeability and low toxicity to Ovcar-8 (IC50: 12.66 µM) and MCF-10A (IC50: 11.72 µM) cells. NDNA3 prevents disruption of hER
Molecular Weight:
476.63
Formula:
C28H32N2O3S
Target:
HSP,Potassium Channel
Application Notes:
Reference compound
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