MCUF-651 is an orally active guanylyl cyclase A receptor (GC-A) positive allosteric modulator (PAM) (KD: 397 nM ). MCUF-651 binds to GC-A and selectively enhances the binding of atrial natriuretic peptide (ANP) to GC-A. MCUF-651 enhances ANP-mediated cGM
Molecular Weight:
368.44
CAS Number:
[2747162-85-0]
Formula:
C17H22F2N4OS
Target:
Guanylate Cyclase
Application Notes:
Reference compound
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