IHMT-PI3K-455 (Compound 15u) is a potent, selective, orally active PI3Kgamma/delta dual inhibitor with IC50s of 7.1 nM and 0.57 nM for PI3Kgamma and PI3Kdelta, respectively. IHMT-PI3K-455 suppresses the AKT phosphorylation. IHMT-PI3K-455 inhibits tumor growth by recruit
Molecular Weight:
517.49
Formula:
C26H21F2N7O3
Target:
PI3K
Application Notes:
Reference compound
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