Nrf2-IN-3 (Compound R16) is a Nrf2 inhibitor. Nrf2-IN-3 binds KEAP1 mutants (G333C mKEAP1) and repairs the disrupted KEAP1/NRF2 interactions. Nrf2-IN-3 sensitizes KEAP1-mutated cancer cells to Cisplatin (HY-17394) and Gefitinib (HY-50895) by repairing th
Molecular Weight:
442.53
Purity:
99.19
CAS Number:
[6325-13-9]
Formula:
C22H26N4O4S
Target:
Keap1-Nrf2
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted