MET/PDGFRA-IN-1 (compound 8c) is a MET and PDGFRA protein inhibitor (IC50: 36 µM for MET). MET/PDGFRA-IN-1 inhibits MET phosphorylation and induces cell apoptosis. MET/PDGFRA-IN-1 inhibits proliferation of MET-positive cells (IC50s: 15.3, 19.0, 22.0, 25.
Molecular Weight:
449.51
Formula:
C26H23N7O
Target:
Apoptosis,c-Met/HGFR,PDGFR
Application Notes:
Reference compound
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