cGAS-IN-1 (compound C20) is a flavonoid and Cyclic GMP-AMP Synthase (cGAS) inhibitor with IC50s of 2.28 µM (human cGAS) and 1.44 µM (mouse cGAS). Abnormal activation of cGAS is associated with a variety of immune-mediated inflammatory diseases, and cGAS-
Molecular Weight:
377.35
Purity:
98.29
CAS Number:
[858770-07-7]
Formula:
C18H19NO8
Target:
Cyclic GMP-AMP Synthase
Application Notes:
Reference compound
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