DNL343 is a brain-penetrating activator of eukaryotic initiation factor 2B (eIF2B) that inhibits the abnormal integrated stress response (ISR). DNL343 inhibits ISR activity in the central nervous system (CNS) and reverses neurodegeneration and neuroinfla
Molecular Weight:
457.83
Purity:
98.91
CAS Number:
[2278265-85-1]
Formula:
C20H19ClF3N3O4
Target:
Eukaryotic Initiation Factor (eIF)
Application Notes:
Reference compound
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