EGFR T790M/L858R-IN-2 is a potent and selective EGFRT790M/L858R inhibitor with IC50 values of 3.5, 1290 nM for EGFRT790M/L858R, EGFR WT, respectively. EGFR T790M/L858R-IN-2 decreases the expression of p-EGFR, P-AKT, P-ERK1/2. EGFR T790M/L858R-IN-2 induce
Molecular Weight:
497.57
Purity:
99.66
CAS Number:
[2955607-40-4]
Formula:
C28H28FN7O
Target:
Apoptosis,EGFR
Application Notes:
Reference compound
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