CDK8-IN-13 is a potent, selective and orally active CDK8 inhibitor with an IC50 value of 51.9 nM. CDK8-IN-13 induces Apoptosis. CDK8-IN-13 decreases the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 shows antitumor activity[1].
Molecular Weight:
237.26
Purity:
99.14
CAS Number:
[918523-75-8]
Formula:
C14H11N3O
Target:
Apoptosis,CDK
Application Notes:
Reference compound
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