EB-47, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM. EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite[1].
Molecular Weight:
537.53
CAS Number:
[366454-36-6]
Formula:
C24H27N9O6
Target:
PARP
Application Notes:
Reference compound
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